人急性髓系白血病细胞Kasumi-6

细胞名称

人急性髓系白血病细胞Kasumi-6

货物编码

BFN60810164

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

90%DMEM+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人急性髓系白血病细胞Kasumi-6取自64岁男性外周血，该细胞源于DSMZ

注释

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: TCGA-110-CL cell line panel.

Population: Japanese and Korean.

Doubling time: ~70 hours (DSMZ).

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Derived from sampling site: Peripheral blood.

基因突变

Heterozygous for CEBPA p.Arg306Pro (c.917G>C) (PubMed=12508245; CCLE).

FLT3 internal tandem duplication (FLT3-ITD) (PubMed=32180206).

Homozygous for TP53 p.Tyr234Asp (c.700T>G) (CCLE).

HLA信息

/

STR信息

Amelogenin        X,Y

CSF1PO        10,12

D5S818        11

D7S820        9,11

D13S317        8,12

D16S539        9,10

TH01        6,9

TPOX        8,9

vWA        17

参考文献

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Nature 569:503-508(2019)

PubMed=31395879; DOI=10.1038/s41467-019-11415-2

Yu K., Chen B., Aran D., Charalel J., Yau C., Wolf D.M., van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.

Nat. Commun. 10:3574-3574(2019)

PubMed=32180206; DOI=10.1007/s13577-020-00347-5

Kasai F., Asou H., Ozawa M., Kobayashi K., Kuramitsu H., Satoh M., Kohara A., Kaneko Y., Kawamura M.

Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.

Hum. Cell 33:0-0(2020)