人膀胱癌细胞VM-CUB-3

细胞名称

人膀胱癌细胞VM-CUB-3

货物编码

BFN6021441

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研用途        3类

培养体系

DMEM高糖（不含丙酮酸钠）+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人膀胱癌细胞VM-CUB-3取自女性供体，贴壁培养。

注释

Problematic cell line: Partially contaminated. Some stocks are contaminated by VM-CUB-1 (PubMed=3708594; PubMed=20143388). Although PubMed=26621286 shows it to be different from VM-CUB-1.

Part of: BLA-40 bladder carcinoma cell line panel.

Part of: UBC-40 urothelial bladder cancer cell line index.

Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00102.

Doubling time: 26 hours (PubMed=3708594).

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

突变信息

TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=24035680).

Homozygous for TP53 p.Pro278Leu (c.833C>T) (ClinVar=VCV000232497) (PubMed=27270441).

STR信息

Amelogenin X

CSF1PO 12

D5S818 11

D7S820 8,9

D13S317 9,12

D16S539 12

TH01 9.3

TPOX 8

vWA 16

参考文献

PubMed=25997541; DOI=10.1186/s12864-015-1450-3

 Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.

 The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

 BMC Genomics 16:403-403(2015)

PubMed=26621286; DOI=10.1186/s12864-015-2227-4

 Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.

 Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

 BMC Genomics 16:1019-1019(2015)

PubMed=27270441; DOI=10.1038/onc.2016.172

 Nickerson M.L., Witte N., Im K.M., Turan S., Owens C., Misner K., Tsang S.X., Cai Z., Wu S., Dean M., Costello J.C., Theodorescu D.

 Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

 Oncogene 36:35-46(2017)

PubMed=29732388; DOI=10.3233/BLC-180167

 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.

 Systematic review: characteristics and preclinical uses of bladder cancer cell lines.

 Bladder Cancer 4:169-183(2018)